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Study identifier: NCT04722029 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pilot Study of Haploidentical Donor Adenovirus Specific T-lymphocytes to Treat Refractory Adenovirus Infections

Condition: Adenovirus Infection  ·  Sponsor: Nationwide Children's Hospital

PhasePhase 1/Phase 2
Planned participants12
Who can joinAll sexes, N/A to 60 Years
Healthy volunteersNo

About this study

This open-label, single-arm, phase I/II clinical trial will assess the safety and efficacy of related donor adenovirus-specific T lymphocytes isolated from whole blood or leukapheresis products. The adenovirus-specific T lymphocytes will be generated automatically by the CliniMACS Prodigy using the CliniMACS Cytokine Capture System (IFN-γ) after incubation with MACS GMP PepTivator Peptide Pools of Hexon 5 for enrichment.

This description comes directly from the study's public registry record.

Talk to the study team

Melinda Triplet  ·  6147226039  ·  Melinda.Triplet@nationwidechildrens.org

Always discuss trial participation with your own doctor first.

Locations (1)

Nationwide Children's HospitalColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04722029