← Eichor
Study identifier: NCT04713722 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Early Life Stress and Depression: Molecular and Functional Imaging

Condition: Depression · Trauma, Psychological  ·  Sponsor: Mclean Hospital

PhaseN/A
Planned participants160
Who can joinFemale, 20 Years to 32 Years
Healthy volunteersYes

About this study

Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity has negative psychological and medical consequences; others preserve mental and physical health despite such experiences (they are resilient). In spite of this, little is known about the neurobiological mechanisms related to childhood adversity, especially oxidative stress abnormalities in the brain. To fill this gap, this study combines functional, structural, and molecular imaging approaches to examine the role of oxidative stress abnormalities related to childhood adversity.

This description comes directly from the study's public registry record.

Talk to the study team

Aliza Brown  ·  617-855-2589  ·  abrown98@mclean.harvard.edu

Emma Palermo  ·  617-855-4412  ·  ehpalermo@mclean.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

McLean HospitalBelmont, Massachusetts, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT04713722