Condition: Glioblastoma · Sponsor: Erasmus Medical Center
The study is designed as an international, multicenter prospective cohort study. Patients with presumed glioblastoma (GBM) in- or near eloquent areas on diagnostic MRI will be selected by neurosurgeons. Patients will be treated following one of three study arms: 1) a craniotomy where the resection boundaries for motor or language functions will be identified by the "awake" mapping technique (awake craniotomy, AC); 2) a craniotomy where the resection boundaries for motor functions will be identified by "asleep" mapping techniques (MEPs, SSEPs, continuous dynamic mapping); 3) a craniotomy where the resection boundaries will not be identified by any mapping technique ("no mapping group"). All patients will receive follow-up according to standard practice.
This description comes directly from the study's public registry record.
Jasper Gerritsen, MD · +31629119553 · j.gerritsen@erasmusmc.nl
Arnaud Vincent, MD PhD · a.vincent@erasmusmc.nl
Always discuss trial participation with your own doctor first.
| University of California, San Francisco | San Francisco, California, United States | Not Yet Recruiting |
| Massachusetts General Hospital | Boston, Massachusetts, United States | Not Yet Recruiting |
| University Hospitals Leuven | Leuven, Vlaams-Brabant, Belgium | Not Yet Recruiting |
| University Hospital Heidelberg | Heidelberg, Germany | Not Yet Recruiting |
| Technical University Munich | Munich, Germany | Not Yet Recruiting |
| Erasmus MC | Rotterdam, South Holland, Netherlands | Recruiting |
| Medical Center Haaglanden | The Hague, South Holland, Netherlands | Not Yet Recruiting |
| Inselspital Universitätsspital Bern | Bern, Switzerland | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT04708171