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Study identifier: NCT04707300 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study Evaluating the Safety and the Efficacy of Human T Lymphoid Progenitor (HTLP) Injection to Accelerate Immune Reconstitution After Umbilical Cord Blood (UCB) Transplantation in Adult Patients With Hematologic Malignancies (HTLP-ONCO)

Condition: Hematologic Malignancy  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 1/Phase 2
Planned participants10
Who can joinAll sexes, 18 Years to 66 Years
Healthy volunteersNo

About this study

This is an open-labelled and non-controlled Phase I/II clinical trial, evaluating the safety and the efficacy of Human T Lymphoid Progenitor (HTLP) injection to accelerate immune reconstitution after umbilical cord blood (UCB) transplantation in adult patients with hematologic malignancies. The dose limiting toxicity of HTLP injection will be evaluated using a model-based design.

This description comes directly from the study's public registry record.

Talk to the study team

Olivier HERMINE, PhD & MD  ·  +33 144495282  ·  olivier.hermine@aphp.fr

Nelly Briand, PhD  ·  01 44 38 18 62  ·  nelly.briand@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (5)

Hôpital Saint LouisParis, FranceRecruiting
Service d'Hématologie et thérapie cellulaire / CHU of BordeauxPessac, FranceRecruiting
IUCT Oncopole ToulouseToulouse, FranceRecruiting
Institut Gustave RoussyVillejuif, FranceNot Yet Recruiting
Hematology department / Necker Children's HospitalParis, Île-de-France Region, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04707300