Condition: Asthma · Sponsor: Chinese University of Hong Kong
Increasing evidence supports that the respiratory microbiota, including viral and bacterial microorganisms, play important roles in respiratory health and disease. Microbial patterns in airways may induce distinctive endotypes of asthma. Previous studies suggest host-microbiota interactions in children may account for the heterogeneity of endotypes and clinical presentations. However, information on such relationship is limited in adults. Furthermore, how the upper airway microbiome is related to asthma endotype and phenotype is not well understood. Knowledge of microbiota in the airway allows exploration of therapeutic manipulation of the microbiome and targeting the development of asthma prevention strategies and the optimization of asthma treatment.
This description comes directly from the study's public registry record.
Fanny Ko, MD · +852 35053133 · fannyko@cuhk.edu.hk
David Hui, MD · +852 35053133 · dschui@cuhk.edu.hk
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| Prince of Wales Hospital | Shatin, Hong Kong | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04706988