● Recruiting

A Randomized Trial of Delayed Radiotherapy in Patients Low-grade Oligodendrogliomas Requiring a Treatment Other Than Surgery

Condition: Oligodendroglioma · Low-grade Oligodendroglioma · 1p19q Codeletion · Sponsor: Hospices Civils de Lyon

PhasePhase 3

Planned participants280

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

Because of their prolonged survival, patients with 1p/19q-codeleted low-grade oligodendrogliomas treated with RT + PCV are at risk of neurocognitive deterioration. We make the hypothesis that withholding radiotherapy until tumor progression could reduce the risk of neurocognitive deterioration without impairing overall survival.

This description comes directly from the study's public registry record.

Talk to the study team

François DUCRAY, MD, PhD · +33(0) 4 72 35 78 06 · francois.ducray@chu-lyon.fr

Cécile TROUBA · +33(0) 4 72 35 69 15 · cecile.trouba@chu-lyon.fr

Always discuss trial participation with your own doctor first.

Locations (26)

CHU d'Amiens-Picardie Site Sud	Amiens, France	Recruiting
Institut de Cancerologie de l'Ouest	Angers, France	Recruiting
CHU de Bordeaux Hôpital Saint André	Bordeaux, France	Recruiting
Institut de Cancérologie et Hematologie (ICH) - CHRU Brest, Hopital Morvan	Brest, France	Recruiting
Hospices Civils de Lyon	Bron, France	Recruiting
CHU de Caen	Caen, France	Not Yet Recruiting
Hôpital d'Instruction des Armées PERCY	Clamart, France	Not Yet Recruiting
Hôpital Pasteur - Hôpitaux civils de Colmar	Colmar, France	Not Yet Recruiting
Centre Georges Francois Leclerc	Dijon, France	Not Yet Recruiting
Hôpital Roger Salengro CHU de Lille	Lille, France	Recruiting
CHU de Limoges	Limoges, France	Not Yet Recruiting
Centre Léon Bérard	Lyon, France	Not Yet Recruiting

+ 14 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04702581