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Study identifier: NCT04699279 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Protective Effect of Statin Against Negative Cardiovascular Remodeling and Organ Dysfunction After Acute Aortic Syndrome Surgery (PANDA III)

Condition: Acute Aortic Syndrome · Aortopathy  ·  Sponsor: Nanjing Medical University

PhaseNA
Planned participants300
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

Acute Aortic Syndrome (AAS)/Aortic Aneurysm is a common feature of aortic wall events, including aortic dissection, intramural hematoma, aortic ulceration and aortic trauma, and occurs in up to 35 cases per 100,000 cases per year between the ages of 65 and 75 years. Increased levels of the inflammatory biomarker high-sensitivity C-reactive protein predict cardiovascular events. Since statins lower levels of high-sensitivity C-reactive protein as well as cholesterol, the authors hypothesized that people with acute aortic syndrome but without hyperlipidemia might benefit from statin treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Hong Liu, MD  ·  18801281613  ·  DR.HONGLIU@FOXMAIL.COM

Yong-feng SHAO, MD  ·  18801281613  ·  YFSHAOJPH@SINA.COM

Always discuss trial participation with your own doctor first.

Locations (5)

The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaRecruiting
The first affiliated hospital of nanjing medical universityNanjing, Jiangsu, ChinaRecruiting
Affiliated Hospital of Qingdao UniversityQingdao, Shandong, ChinaRecruiting
West China Hospital of Sichuan UniversityChengdu, Sichuan, ChinaRecruiting
Beijing Anzhen HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04699279