Condition: Transfer Dysphagia · Oropharyngeal Dysphagia · Cricopharyngeus Muscle Dysfunction · Sponsor: All India Institute of Medical Sciences
Dysphagia in patients with stroke, multiple sclerosis, parkinsonism or dystonia can occur due to relative hypertonia of the cricopharyngeus muscle. In the resting state, muscle is contracted and relaxes only during deglutition. Treatment of dysphagia by injecting botulinum toxin in the cricopharyngeus was described by Schneider et al. in 1994. More than 100 cases have been described after that, however there are no randomized controlled trials. A meta-analysis from Cochrane has also concluded that there is no sufficient evidence to conclude regarding the efficacy and safety of Botulinum toxin injection in cricopharyngeal dysfunction. So this study is necessary to fill this void in knowledge
This description comes directly from the study's public registry record.
Arunmozhimaran Elavarasi, MD DM · +919013844274 · arun_ela@yahoo.com
Pramod Garg, MD DM · +919810038116 · pkgarg@aiims.ac.in
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| All India Institute of Medical Sciences, New Delhi | New Delhi, National Capital Territory of Delhi, India | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04695600