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Study identifier: NCT04691622 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts

Condition: Viral Infection · Hematopoietic Stem Cell Transplantation (HSCT) · Primary Immunodeficiency Disorders (PID)  ·  Sponsor: Children's National Research Institute

PhasePhase 1
Planned participants48
Who can joinAll sexes, 3 Months to 80 Years
Healthy volunteersNo

About this study

This is a Phase I dose-escalation study to evaluate the safety of norovirus -specific T-cell (NST) therapy for chronic norovirus infection in participants following hematopoietic stem cell transplantation (HSCT) or who are immunocompromised due to PID and have not undergone HSCT, or Solid Organ Transplant (SOT) recipients.

This description comes directly from the study's public registry record.

Talk to the study team

Michael Keller, MD  ·  202-476-5843  ·  MKeller@childrensnational.org

Fahmida Hoq, MBBS, MS  ·  202-476-3634  ·  fhoq@childrensnational.org

Always discuss trial participation with your own doctor first.

Locations (3)

Children's National HospitalWashington D.C., District of Columbia, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
National Institutes of Health (NIH)Bethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04691622