Condition: Esophageal Cancer · Gastroesophageal Cancer · Immunotherapy · Sponsor: The Second Hospital of Shandong University
Surgery with or without neoadjuvant therapy is usually used as the treatment for resectable esophageal cancer or esophageal- gastric junction cancer. Patients who have a poor response to neoadjuvant therapy and have an incomplete (R1) resection or have metastatic lymph nodes in the resection specimen (N+) are especially at risk of recurrence, to continue with the chemotherapy± radiotherapy is often used in these cases. However, the overall survival is still poor. We designed a prospective randomized controlled tial to study whether immunotherapy could be used with chemotherapy after surgery to improve overall survival. The primary endpoint ofthe study is disease free survival, with secondary endpoints of overall survival, safety and toxicity, and quality of life.
This description comes directly from the study's public registry record.
Yunpeng Zhao, Doc. · +8617660081916 · zhaoyunpengsddx@sdu.edu.cn
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| The Second Hospital of Shandong University | Jinan, Shandong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04688801