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Study identifier: NCT04688190 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

Condition: Mitral Regurgitation · Mitral Valve Disease · Mitral Annular Calcification  ·  Sponsor: Universitätsklinikum Hamburg-Eppendorf

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This multinational, investigator-initiated registry aims to investigate clinical outcomes of patients undergoing transcatheter mitral valve replacement (TMVR). The registry primarily focuses on patients treated with TMVR in real-world clinical practice. Patients evaluated for TMVR but not undergoing the procedure are no longer systematically included. Historical data may include such patients who subsequently underwent alternative treatments, including transcatheter edge-to-edge repair, mitral valve surgery, or medical/conservative therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Sebastian Ludwig, MD  ·  +494074100  ·  se.ludwig@uke.de

Lena Strotmann, MD  ·  +4074100  ·  L.Strotmann@uke.de

Always discuss trial participation with your own doctor first.

Locations (43)

Tucson Medical CenterTucson, Arizona, United StatesRecruiting
Cedars-Sinai Medical Center, Los AngelesLos Angeles, California, United StatesRecruiting
Tampa General HospitalTampa, Florida, United StatesRecruiting
Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting
Minneapolis Heart Institute at Abbott Northwestern HospitalMinneapolis, Minnesota, United StatesRecruiting
Morristown Medical CenterMorristown, New Jersey, United StatesRecruiting
Montefiore Medical CenterNew York, New York, United StatesRecruiting
Oklahoma Heart HospitalOklahoma City, Oklahoma, United StatesRecruiting
Houston Methodist HospitalHouston, Texas, United StatesRecruiting
St Vincent's HospitalSydney, AustraliaRecruiting
Medical University of ViennaVienna, AustriaRecruiting
Québec Heart and Lung Institute (Laval University)Québec, Quebec, CanadaRecruiting

+ 31 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04688190