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Study identifier: NCT04686682 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors

Condition: NSCLC · SCLC · CRPC  ·  Sponsor: Jacobio Pharmaceuticals Co., Ltd.

PhasePhase 1/Phase 2
Planned participants152
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1/2a, first-in-human, open-label study of JAB-8263, this study has two parts: solid tumor dose escalation and expansion study and hematology tumor dose escalation and expansion study. These two parts will determine the maximum tolerated dose (MTD), recommended Phase 2 dose (RP2D) and assess the DLT of JAB-8263 in treatment with patients with advanced solid tumors and hematology tumors separately. 30 subjects each will be enrolled.

This description comes directly from the study's public registry record.

Talk to the study team

Jacobio Pharmaceuticals  ·  86 10 56315466  ·  clinicaltrials@jacobiopharma.com

Always discuss trial participation with your own doctor first.

Locations (1)

TianjinTianjin, Tianjin Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04686682