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Study identifier: NCT04682158 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma

Condition: Esophageal Adenocarcinoma  ·  Sponsor: Roswell Park Cancer Institute

PhasePhase 2
Planned participants106
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies the side effects and best dose of propranolol when administered concurrently with SOC neoadjuvant CRT in patients with esophageal carcinoma, with a safety lead-in and dose expansion cohort. Patients who are already on β-blockers will receive standard of care CRT, or definitive chemotherapy or chemotherapy-immunotherapy and will be considered separately as a single arm prospective cohort

This description comes directly from the study's public registry record.

Talk to the study team

ASK RPCI  ·  1-800-767-9355  ·  askroswell@roswellpark.org

Always discuss trial participation with your own doctor first.

Locations (1)

Roswell Park Cancer InstituteBuffalo, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04682158