Condition: Retinoblastoma · Sponsor: Institut Curie
This protocol includes 2 independent studies. Both studies are multicenter studies, evaluating different therapeutic approaches in two different populations of patients: * Study 1, a randomized phase-II study evaluating the efficacy of Intra-Arterial Chemotherapy (IAC) with melphalan and topotecan versus melphalan alone, both in association with ophthalmologic treatments. * Study 2, a minimally invasive interventional study evaluating the results on visual function following reference treatment with intravenous (IV) chemotherapy in association with ophthalmologic or local ophthalmological treatment without IV chemotherapy.
This description comes directly from the study's public registry record.
Livia LUMBROSO LE ROUIC, MD · +33(0)144324163 · livia.lumbroso-lerouic@curie.fr
Christine FOULON, PhD · +33(0)147111733 · drci.promotion@curie.fr
Always discuss trial participation with your own doctor first.
| La Reunion - Chr Felix Guyon | Saint-Denis, La Réunion, France | Recruiting |
| Amiens Chu | Amiens, France | Recruiting |
| Angers Chu | Angers, France | Recruiting |
| BESANCON CHU Hopital Jean Minjoz | Besançon, France | Recruiting |
| Bordeaux Chu | Bordeaux, France | Recruiting |
| BREST CHRU Hopital Morvan | Brest, France | Recruiting |
| CAEN CHU | Caen, France | Recruiting |
| CHU ESTAING Centre Régional de Cancérologie et Therapie Cellulaire Pediatrique (CRCTCP) | Clermont-Ferrand, France | Recruiting |
| DIJON CHU Hopital François Mitterand | Dijon, France | Recruiting |
| Grenoble Chu | Grenoble, France | Recruiting |
| LILLE Centre Oscar Lambret | Lille, France | Recruiting |
| Limoges Chu | Limoges, France | Recruiting |
+ 16 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04681417