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Study identifier: NCT04677816 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients

Condition: Triple Negative Breast Cancer · Vitamin D Deficiency · Invasive Breast Cancer  ·  Sponsor: Wake Forest University Health Sciences

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A two arm pilot study investigating the rate of pathologic complete response in patients with vitamin D deficiency and triple negative breast cancer undergoing standard neoadjuvant chemotherapy + vitamin D supplementation, including an observational arm to describe response in patients who are not deficient. Investigators hypothesize that vitamin D supplementation during neoadjuvant chemotherapy in operable triple negative breast cancer patients with vitamin D deficiency, will increase the rate of pathologic complete response chain reaction to that of vitamin D sufficient patients based on historical controls.

This description comes directly from the study's public registry record.

Talk to the study team

Study Coordinator  ·  336-713-0031  ·  jwyche@wakehealth.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Wake Forest Baptist Health SciencesWinston-Salem, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04677816