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Study identifier: NCT04676802 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

Condition: Pain, Postoperative · Osteoarthritis Thumb  ·  Sponsor: Stanford University

PhasePhase 2
Planned participants121
Who can joinAll sexes, 45 Years to no upper limit
Healthy volunteersNo

About this study

In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Deborah Kenney, MS OTR  ·  6507217644  ·  dkenney@stanford.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Stanford Health CareRedwood City, California, United StatesRecruiting
University of Utah Health CareSalt Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04676802