Condition: Prosthetic Infection · Sponsor: Tourcoing Hospital
Rifampicin, is key in the treatment of staphylococcal PJIs. Rifabutin has a better profile of tolerance than rifampicin regarding the risk of interaction with concomitant medications and liver disorders. The hypothesis is that rifabutin may be an alternative antibiotic option as efficient as rifampicin for the treatment of staphylococcal PJIs, with a better safety profile. The investigator aim to demonstrate the non-inferiority of rifabutin as compared with rifampicin prescribed in combination treatment for PJIs.
This description comes directly from the study's public registry record.
Eric SENNEVILLE, MD PhD · 0320694949 · esenneville@ch-tourcoing.fr
Solange TREHOUX · 0320694280 · strehoux@ch-tourcoing.fr
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| CHU Amiens Picardie | Amiens, France | Not Yet Recruiting |
| CHU Angers | Angers, France | Not Yet Recruiting |
| CHU Besançon | Besançon, France | Recruiting |
| CH de Béthune | Béthune, France | Not Yet Recruiting |
| CHU Bordeaux | Bordeaux, France | Not Yet Recruiting |
| APHP Hôpital Ambroise Paré | Boulogne-Billancourt, France | Not Yet Recruiting |
| CHRU Brest | Brest, France | Recruiting |
| CHU Caen | Caen, France | Recruiting |
| CH Alpes Leman | Contamine-sur-Arve, France | Not Yet Recruiting |
| CHU Dijon Bourgogne | Dijon, France | Not Yet Recruiting |
| CHU Grenoble Alpes | Grenoble, France | Not Yet Recruiting |
| CHRU Lille | Lille, France | Recruiting |
+ 18 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04672525