Condition: Advanced Lung Neuroendocrine Tumor · Functioning Lung Neuroendocrine Tumor · Locally Advanced Lung Neuroendocrine Neoplasm · Sponsor: National Cancer Institute (NCI)
This phase II trial studies the effect of lutetium Lu 177 dotatate compared to the usual treatment (everolimus) in treating patients with somatostatin receptor positive bronchial neuroendocrine tumors that have spread to other places in the body (advanced). Lutetium Lu 177-dotate is a radioactive drug. It binds to a protein called somatostatin receptor, which is found on some neuroendocrine tumor cells. Lutetium Lu 177-dotatate builds up in these cells and gives off radiation that may kill them. It is a type of radioconjugate and a type of somatostatin analog. Lutetium Lu 177 dotatate may be more effective than everolimus in shrinking or stabilizing advanced bronchial neuroendocrine tumors.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
Always discuss trial participation with your own doctor first.
| University of Alabama at Birmingham Cancer Center | Birmingham, Alabama, United States | Withdrawn |
| Tower Cancer Research Foundation | Beverly Hills, California, United States | Recruiting |
| Loma Linda University Medical Center | Loma Linda, California, United States | Suspended |
| Cedars-Sinai Medical Center | Los Angeles, California, United States | Recruiting |
| UCSF Medical Center-Mission Bay | San Francisco, California, United States | Recruiting |
| Torrance Memorial Physician Network - Cancer Care | Torrance, California, United States | Recruiting |
| MedStar Georgetown University Hospital | Washington D.C., District of Columbia, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Aventura | Aventura, Florida, United States | Suspended |
| UM Sylvester Comprehensive Cancer Center at Coral Gables | Coral Gables, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach, Florida, United States | Recruiting |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami, Florida, United States | Recruiting |
| UM Sylvester Comprehensive Cancer Center at Plantation | Plantation, Florida, United States | Recruiting |
+ 17 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04665739