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Study identifier: NCT04662658 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Hyperpolarized Xenon-129 MR Imaging of the Lung

Condition: E-Cig Use  ·  Sponsor: University of Virginia

PhasePhase 1/Phase 2
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Over the past 10 years, electronic cigarettes (e-cigarettes, EC) have been commercialized as a "less harmful" alternative to traditional cigarettes.1,2 However, e-cigarettes are believed to cause pulmonary epithelial, endothelial and vascular dysfunction, and to cause murine phenotypes similar to those of human COPD. Recently, "spiked" vape juice has been linked to severe lung damage. Unfortunately, the effects of e-cigarettes on the human lungs are still poorly understood, especially in healthy young adults. Therefore, establishing the health effects of e-cigarettes in humans is of paramount importance to guide medical and regulatory decision making. Its widespread use and immense popularity among teenagers and young adults have caused major concern given potentially significant addictive and detrimental long-term health effects.

This description comes directly from the study's public registry record.

Talk to the study team

Roselove Asare  ·  434-243-6074  ·  rnn3b@virginia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Snyder Building 480 Ray C. Hunt DriveCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04662658