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Study identifier: NCT04661280 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Donepezil Versus Non-drug Treatment in Alzheimer's Disease.

Condition: Alzheimer Disease, Early Onset  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants240
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Donepezil, as well as the other symptomatic drugs of Alzheimer's disease, is not any more reimbursed by the French healthcare system, due to a controversy about its efficiency. French health authorities currently preconize a non-rug approach based on cognitive remediation or stimulation. The aim of this study is to compare the efficiency of the 2 approaches (non-drug versus donepezil) on the symptoms of Alzheimer's disease after 6 months of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

DUMURGIER Julien, MD, PhD  ·  +33140054313  ·  julien.dumurgier@aphp.fr

PAQUET Claire, MD, PhD  ·  claire.paquet@inserm.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Cognitive Neurology CenterParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT04661280