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Study identifier: NCT04657822 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

Condition: Sickle Cell Disease  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 4
Planned participants130
Who can joinAll sexes, 6 Months to 100 Years
Healthy volunteersNo

About this study

This is a multi-center multi-national rollover study to allow continued access to crizanlizumab for patients with sickle cell disease (SCD) who are on crizanlizumab treatment in a Novartis-sponsored study (parent study) and are benefiting from the treatment as judged by the investigator.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (31)

University Of AlabamaBirmingham, Alabama, United StatesRecruiting
Childrens National HospitalWashington D.C., District of Columbia, United StatesActive Not Recruiting
Augusta University GeorgiaAugusta, Georgia, United StatesRecruiting
East Carolina UniversityGreenville, North Carolina, United StatesCompleted
East Carolina UniversityGreenville, North Carolina, United StatesCompleted
Childrens Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesActive Not Recruiting
Cook Childrens Medical CenterFort Worth, Texas, United StatesCompleted
Novartis Investigative SiteBrussels, BelgiumCompleted
Novartis Investigative SiteLaken, BelgiumActive Not Recruiting
Novartis Investigative SiteLiège, BelgiumActive Not Recruiting
Novartis Investigative SiteSalvador, Estado de Bahia, BrazilActive Not Recruiting
Novartis Investigative SiteRibeirão Preto, São Paulo, BrazilActive Not Recruiting

+ 19 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04657822