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Study identifier: NCT04646252 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Role of Glycocalyx Integrity in the Primary Prevention of Major Cardiovascular Events

Condition: Endothelial Dysfunction · Arterial Stiffness  ·  Sponsor: University of Athens

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersYes

About this study

The researchers intend to recruit individuals who are referred for a routine screening in the primary prevention outpatient clinic of Attikon University hospital, Athens According to institutional protocols, a detailed medical history for atherosclerotic risk factors and current medication is recorded and a baseline clinical examination is performed. Moreover fasting blood samples are drawn to diagnose the presence of diabetes mellitus and hyperlipidemia. Glycocalyx examination is performed at the same visit. The subjects are revaluated at one month and then followed up according to the attending physician's instructions. Pulse wave velocity and the rest pulse wave analysis parameters were also calculated to determine the additive predictive value for cardiovascular events beyond SCORE2. All subjects are followed up for adverse events (death, stroke, myocardial infarction, hospitalization for heart failure) for 6 years after enrollment via telephonic contact and planned appointment at the outpatient clinic.

This description comes directly from the study's public registry record.

Talk to the study team

IGNATIOS IKONOMIDIS  ·  +30 2105832192  ·  ignoik@gmail.com

John Thymis  ·  +306940617712  ·  johnythg@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

"Attikon" University General HospitalAthens, Attica, GreeceRecruiting

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Source record: clinicaltrials.gov/study/NCT04646252