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Study identifier: NCT04643002 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Isatuximab in Combination With Novel Agents in RRMM - Master Protocol

Condition: Plasma Cell Myeloma Refractory  ·  Sponsor: Sanofi

PhasePhase 1/Phase 2
Planned participants258
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this umbrella study is to evaluate isatuximab when combined with novel agents with or without dexamethasone in participants with relapsed or refractory myeloma. Substudy 01 is the control Substudy. Substudies 02, 03, and 06 are controlled experimental substudies. Substudies 04 and 05 are independent experimental substudies.

This description comes directly from the study's public registry record.

Talk to the study team

Trial Transparency email recommended (Toll free number for US & Canada)  ·  800-633-1610  ·  contact-us@sanofi.com

Always discuss trial participation with your own doctor first.

Locations (26)

Winship Cancer Institute of Emory University- Site Number : 8400010Atlanta, Georgia, United StatesRecruiting
University of Illinois-Chicago - College of Medicine- Site Number : 8400007Chicago, Illinois, United StatesCompleted
University of Michigan Health System - Ann Arbor- Site Number : 8400004Ann Arbor, Michigan, United StatesRecruiting
Roswell Park Cancer Institute- Site Number : 8400008Buffalo, New York, United StatesRecruiting
The Ohio State University- Site Number : 8400012Columbus, Ohio, United StatesRecruiting
Investigational Site Number : 0360006Wollongong, New South Wales, AustraliaRecruiting
Investigational Site Number : 0360002Melbourne, Victoria, AustraliaRecruiting
Investigational Site Number : 0360001Richmond, Victoria, AustraliaRecruiting
Investigational Site Number : 2500003Paris, Washington, FranceRecruiting
Investigational Site Number : 2500002Lille, FranceRecruiting
Investigational Site Number : 2500001Nantes, FranceRecruiting
Investigational Site Number : 2500004Paris, FranceRecruiting

+ 14 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04643002