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Study identifier: NCT04639336 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cognitive and Neurological Pathologies in Pompe Disease

Condition: Pompe Disease  ·  Sponsor: Duke University

PhaseN/A
Planned participants45
Who can joinAll sexes, 0 Years to 18 Years
Healthy volunteersNo

About this study

The purpose of this study is to better understand the long-term health effects of Pompe disease and to determine if there are any abnormal changes in the brain and peripheral nerves. Additionally, the investigators will study the relationship between the abnormal changes in brain, nervous system findings, and developmental outcomes. The investigators will collect clinical information from clinic visits as well as assessments such as neuroimaging (magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), and diffusion tensor imaging (DTI)), cognition, academic skills, speech and language function, physical therapy and quantitative muscle ultrasound. Subjects will be in this study for at least 3 years and up to 6 years.

This description comes directly from the study's public registry record.

Talk to the study team

Gretchen Nichting  ·  +1 919 660 0757  ·  gretchen.nichting@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke University Medical CenterDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04639336