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Study identifier: NCT04637620 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

NMDA Modulation in Major Depressive Disorder

Condition: Major Depressive Disorder  ·  Sponsor: China Medical University Hospital

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

Most of the current antidepressants for major depressive disorder (MDD) are based upon the monoamine hypothesis which cannot fully explain the etiology of depression. NMDA hypofunction has been implicated in the pathophysiology of depression. Therefore, this study will examine the efficacy and safety as well as cognitive function improvement of an NMDA enhancer (NMDAE) in the treatment of MDD in the adults.

This description comes directly from the study's public registry record.

Talk to the study team

Hsien-Yuan Lane, M.D., Ph.D  ·  886 4 22052121  ·  hylane@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Psychiatry, China Medical University HospitalTaichung, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT04637620