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Study identifier: NCT04629833 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Treatment Of Steroid-Refractory Acute Graft-versus-host Disease With Mesenchymal Stromal Cells Versus Best Available Therapy

Condition: Steroid-refractory Acute Graft-versus-host Disease  ·  Sponsor: medac GmbH

PhasePhase 3
Planned participants210
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The primary purpose of this trial is to demonstrate the superiority of MC0518 compared to the first used best available therapy (BAT) with respect to overall response rate (ORR) at Day 28 and/or overall survival (OS) until Visit Month 24 in adult and adolescent subjects with steroid-refractory acute graft-versus-host disease (SR-aGvHD).

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trial Information  ·  +49 40103 8006-0  ·  ClinicalTrialInformation@medac.de

Always discuss trial participation with your own doctor first.

Locations (42)

Centre Hospitalier Universitaire (CHU) Amiens-Picardie - Hopital SudAmiens, FranceRecruiting
CHU Jean MinjozBesançon, FranceRecruiting
Hopital MichallonGrenoble, FranceRecruiting
CHRU Lille- Hopital Claude HuriezLille, FranceRecruiting
CHU de Nantes - Hotel DieuNantes, FranceRecruiting
CHU de Nice Hopital Archet 1Nice, FranceRecruiting
Centre Hospitalier Lyon Sud Pavillon Marcel Berard 1GPierre-Bénite, FranceRecruiting
Centre Hospitalier Universitaire CHU de ToulouseToulouse, FranceRecruiting
Hopitaux De BraboisVandœuvre-lès-Nancy, FranceRecruiting
Klinikum rechts der IsarMunich, Bavaria, GermanyRecruiting
Universitaetsklinikum Wuerzburg - Medizinische Klinik und Poliklinik II - Zentrum fuer Allogene BlutstammzelltransplantationWürzburg, Bavaria, GermanyRecruiting
Klinikum der Johann Wolfgang Goethe-Universitaet - Frankfurt am MainFrankfurt am Main, Hesse, GermanyRecruiting

+ 30 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04629833