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Study identifier: NCT04625023 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Master Protocol Empowering Mechanobiology Translation Research in Breast Cancer

Condition: Breast Cancer  ·  Sponsor: IFOM ETS - The AIRC Institute of Molecular Oncology

PhaseN/A
Planned participants1500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

METAMECH is a master observational protocol designed to empower a bi-directional collaboration between basic and clinical research, an essential prerequisite to feed and implement precision oncology. METAMECH will follow a stage-mixed cohort of at least 500 patients through their course of treatments, until death or a minimum of 5 years. Patients will be longitudinally sampled and matched clinical data (including imaging) will be collected. Via a multi-tiered informed consensus process, METAMECH will also allow to develop companion diagnostics for molecular enrichment strategies in AIRC-driven proof-of-concept trials.

This description comes directly from the study's public registry record.

Talk to the study team

Smeralda Rapisarda  ·  +3902574303236  ·  clinical.trials@ifom.eu

Ylenia Silvestri, PhD  ·  +3902574303799  ·  clinical.trials@ifom.eu

Always discuss trial participation with your own doctor first.

Locations (10)

Asst Papa Giovanni XxiiiBergamo, Bergamo, ItalyNot Yet Recruiting
Fondazione IRCCS, Istituto Nazionale dei TumoriMilan, Milan, ItalyRecruiting
Fondazione IRCCS, Istituto Neurologico Carlo BestaMilan, Milan, ItalyRecruiting
Azienda Ospedaliero Universitaria Maggiore della Carità di NovaraNovara, Novara, ItalyRecruiting
Istituto Oncologico Veneto IRCCS (IOV)Padova, Padova, ItalyRecruiting
Fondazione IRCCS, Policlinico San Matteo PaviaPavia, Pavia, ItalyRecruiting
Istituto Nazionale Tumori Regina Elena di Roma - Istituti Fisioterapici Ospitalieri (IFO)Roma, Roma, ItalyRecruiting
IRCCS HumanitasMilan, ItalyRecruiting
IEO - Istituto Europeo di OncologiaMilan, ItalyRecruiting
Azienda U.S.L. - IRCCS di Reggio EmiliaReggio Emilia, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT04625023