Condition: Diagnosed or Relapsed/Refractory Sarcomas · Sponsor: Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna
Bone and soft tissue sarcomas represent about 7-12% of all pediatric cancer and are a heterogeneous group of tumors arising in connective tissues embryologically derived from the mesenchyme. For some of these tumors relapse and mortality rates are still significantly high. Therefore, further studies are needed to better understand pathogenetic processes underlying sarcomas to offer new and more effective treatments. Next generation sequencing (NGS) has opened new frontiers for cancer research allowing to identify somatic or constitutional mutations known or yet unknown with the aim to better understand carcinogenesis. The establishment of the genomic profile of the tumor could also help clinicians to personalize patients treatment based on their genetic and molecular alterations.
This description comes directly from the study's public registry record.
Elisa Tirtei, MD · 00390113135171 · etirtei@cittadellasalute.to.it
Celeste Cagnazzo, PhD · celeste.cagnazzo@unito.it
Always discuss trial participation with your own doctor first.
| AOU Città della Salute e della Scienza di Torino - Presidio Infantile Regina Margherita | Torino, Turin, Italy | Recruiting |
| Istituto Ortopedico Rizzoli | Bologna, Italy | Recruiting |
| Policlinico S.Orsola-Malpighi | Bologna, Italy | Recruiting |
| Azienda ospedaliero-universitaria Meyer | Florence, Italy | Recruiting |
| Istituto Giannina Gaslini | Genova, Italy | Recruiting |
| Istituto Nazionale Tumori | Milan, Italy | Recruiting |
| Presidio Ospedaliero Gaetano Pini | ASST Pini-CTO | Milan, Italy | Suspended |
| Fondazione I.R.C.C.S. Policlinico San Matteo | Pavia, Italy | Recruiting |
| Istituti fisioterapici Ospitalieri - Istituto Tumori Regina Elena e Istituto Dermatologico San Gallicano | Roma, Italy | Active Not Recruiting |
| IRCCS materno infantile Burlo Garofolo | Trieste, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04621201