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Study identifier: NCT04616586 Synced from ClinicalTrials.gov · July 28, 2026
● Terminated

SILtuximab in Viral ARds (SILVAR) Study

Condition: Acute Respiratory Distress Syndrome · Lung Diseases · Pneumonia  ·  Sponsor: RECORDATI GROUP

PhasePhase 3
Planned participants555
Who can joinAll sexes, 12 Years to 65 Years
Healthy volunteersNo

About this study

This study will evaluate the efficacy and safety of siltuximab compared with normal saline in combination with standard of care (SOC) in selected hospitalized patients with COVID-19 previously treated with corticosteroids or another respiratory virus infection associated with acute respiratory distress syndrome (ARDS) and elevated C-reactive protein (CRP) levels.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (2)

Sparrow Clinical Research InstituteLansing, Michigan, United States
Atrium HealthCharlotte, North Carolina, United States

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Source record: clinicaltrials.gov/study/NCT04616586