Condition: Critical Illness · Osteoporosis · Sponsor: Australian and New Zealand Intensive Care Research Centre
The Bone Zone trial is a prospective, multi-centre, double-blind, phase II, randomised controlled trial evaluating the effect of denosumab or zoledronic acid compared to placebo on change in bone mineral density over one year in women aged 50 years or older and men aged 70 years or older requiring admission to intensive care for greater than 24 hours. 450 women aged 50 years or older and men aged 70 years or older, admitted to intensive care for greater than 24 hours will be recruited into the study from participating study centres.
This description comes directly from the study's public registry record.
Allison Bone · +61 3 9903 0343 · allison.bone@monash.edu
Tony Trapani · +61 3 9903 0343 · tony.trapani@monash.edu
Always discuss trial participation with your own doctor first.
| St Vincent's Health Sydney | Sydney, New South Wales, Australia | Recruiting |
| Prince of Wales Hospital | Sydney, New South Wales, Australia | Recruiting |
| Blacktown Hospital | Sydney, New South Wales, Australia | Recruiting |
| Royal Prince Alfred Hospital | Sydney, New South Wales, Australia | Recruiting |
| Wollongong Hospital, Illawarra Shoalhaven Health | Wollongong, New South Wales, Australia | Recruiting |
| Sunshine Coast University Hospital | Birtinya, Queensland, Australia | Recruiting |
| The Wesley Hospital | Brisbane, Queensland, Australia | Recruiting |
| Gold Coast University Hospital | Southport, Queensland, Australia | Recruiting |
| Royal Adelaide Hospital | Adelaide, South Australia, Australia | Recruiting |
| Barwon Health, University Hospital Geelong | Geelong, Victoria, Australia | Recruiting |
| Alfred Health | Melbourne, Victoria, Australia | Completed |
| Western Health - Footscray Hospital | Melbourne, Victoria, Australia | Recruiting |
+ 10 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04608630