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Study identifier: NCT04603222 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Evaluation of SUMMIT BRUSH in Treatment of Blepharitis

Condition: Blepharitis  ·  Sponsor: University of Notre Dame

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

Dry Eye Disease (DED) is a multifactorial disease that affects \~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity in the workplace, and affects the quality of lives of the people affected by this disease. DED is primarily caused by blepharitis, a chronic inflammation of the eyelid margins. If left untreated, blepharitis results in the obstruction and loss of the glands responsible for tear film production. The standard of care is the use of self-administered at home commercially available products, e.g., eyelid foams, gels, and pads. Although these products are helpful, they have limitations. Patients often require expensive in office procedures, e.g., lid debridement with exfoliation devices or more expensive procedures. The scope of this project is to evaluate the effectiveness of a new self-administered disposable ocular brush used in conjunction with the most common eyelid cleanser. The investigators are looking to see if combining the microexfoliation provided by the brush with the eyelid cleanser is more effective at removing the eyelid debris than the cleanser alone.

This description comes directly from the study's public registry record.

Talk to the study team

Giles E Duffield, Ph.D.  ·  5746311834  ·  duffield.2@nd.edu

Always discuss trial participation with your own doctor first.

Locations (3)

University of ColoradoBoulder, Colorado, United StatesRecruiting
Michiana Eye CenterMishawaka, Indiana, United StatesRecruiting
Kentucky Eye InstituteLexington, Kentucky, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04603222