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Study identifier: NCT04598009 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

Condition: Melanoma Stage III · Melanoma Stage IV  ·  Sponsor: University of California, San Francisco

PhasePhase 2
Planned participants25
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies how well binimetinib and imatinib work in treating patients with stage III-IV KIT-mutant melanoma that cannot be removed by surgery (unresectable). Binimetinib and imatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving binimetinib and imatinib may help treat patients with KIT-mutant melanoma.

This description comes directly from the study's public registry record.

Talk to the study team

Sonia Contreras Martinez  ·  (415) 514-6427  ·  sonia.contrerasmartinez@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (2)

UC San Diego Moores Cancer CenterLa Jolla, California, United StatesRecruiting
University of California, San FranciscoSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04598009