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Study identifier: NCT04592445 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

Condition: Heart Failure With Preserved Ejection Fraction (HFpEF  ·  Sponsor: Axon Therapies, Inc.

PhaseNA
Planned participants150
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this clinical study is to evaluate the safety and early effectiveness of a catheter-based procedure that treats a nerve called the right greater splanchnic nerve. The study includes people who have heart failure with preserved ejection fraction (HFpEF). The goal is to learn whether this procedure, performed using the Satera Ablation System, may help improve symptoms and to better understand which patients may benefit most from this treatment in the future.

This description comes directly from the study's public registry record.

Talk to the study team

Judit Adorjan  ·  16507221119  ·  j.adorjan@axontherapies.com

Jennifer Moore, MS  ·  jennifer@axontherapies.com

Always discuss trial participation with your own doctor first.

Locations (20)

Cardiology PCBirmingham, Alabama, United StatesCompleted
Arizona Cardiovascular Research CenterPhoenix, Arizona, United StatesActive Not Recruiting
Scripps HealthLa Jolla, California, United StatesActive Not Recruiting
University of California, San FranciscoSan Francisco, California, United StatesRecruiting
Bluhm Cardiovascular Institute of Northwestern UniversityChicago, Illinois, United StatesRecruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
Prairie Education and Research CooperativeSpringfield, Illinois, United StatesActive Not Recruiting
Ascension St. Vincent - Cardiovascular Research InstituteIndianapolis, Indiana, United StatesCompleted
Cardiovascular Institute of the SouthHouma, Louisiana, United StatesRecruiting
Michigan Medicine, University of MichiganAnn Arbor, Michigan, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
St. Louis Heart and VascularSt Louis, Missouri, United StatesRecruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04592445