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Study identifier: NCT04588311 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients

Condition: Trauma · Traumatic Injury · Traumatic Brain Injury  ·  Sponsor: Australian and New Zealand Intensive Care Research Centre

PhasePhase 3
Planned participants2500
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The EPO-TRAUMA study is a prospective, multi-centre, double-blind, phase III, randomised controlled trial evaluating the efficacy of epoetin alfa compared to placebo in reducing mortality and severe disability at six months in critically ill trauma patients. 2500 mechanically ventilated ICU patients admitted with a primary trauma diagnosis presenting to the ICU will be recruited into the study from participating study centres in Australia, New Zealand, Europe, and Saudi Arabia.

This description comes directly from the study's public registry record.

Talk to the study team

Vicki Papanikolaou  ·  +61 409 142 695  ·  vicki.papanikolaou@monash.edu

Sian Donnelly  ·  +353 (1) 716 5810  ·  sian.donnelly@ucd.ie

Always discuss trial participation with your own doctor first.

Locations (41)

Royal Prince Alfred HospitalCamperdown, New South Wales, AustraliaRecruiting
St Vincent's Hospital SydneyDarlinghurst, New South Wales, AustraliaActive Not Recruiting
St George HospitalKogarah, New South Wales, AustraliaRecruiting
Liverpool HospitalLiverpool, New South Wales, AustraliaRecruiting
John Hunter HospitalNew Lambton Heights, New South Wales, AustraliaRecruiting
Royal North Shore HospitalSaint Leonards, New South Wales, AustraliaRecruiting
Westmead HospitalWestmead, New South Wales, AustraliaRecruiting
Royal Darwin HospitalTiwi, Northern Territory, AustraliaNot Yet Recruiting
Cairns HospitalCairns, Queensland, AustraliaWithdrawn
Royal Brisbane and Women's HospitalHerston, Queensland, AustraliaRecruiting
Gold Coast University HospitalSouthport, Queensland, AustraliaRecruiting
Princess Alexandra HospitalWoolloongabba, Queensland, AustraliaRecruiting

+ 29 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04588311