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Study identifier: NCT04587856 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Molecular Mechanisms of Disease Relapse After Allogenic Stem Cell Transplantation in MDS Patients

Condition: Myelodysplastic Syndromes  ·  Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto

PhaseNA
Planned participants38
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a biological study for adult MDS patients who undergo HSCT procedure. Viable bone marrow samples will be collected and cryopreserved from MDS patients before transplantation and at clinical disease recurrence. CD34+ blast cells at disease relapse after HSCT will be compared with CD34+ cells collected before transplant to study genomic and transcriptomic changes.

This description comes directly from the study's public registry record.

Talk to the study team

Paola Fazi  ·  0670390528  ·  p.fazi@gimema.it

Enrico Crea  ·  0670390514  ·  e.crea@gimema.it

Always discuss trial participation with your own doctor first.

Locations (7)

Aou Consorziale Policlinico - Bari - Uo Ematologia Con TrapiantoBari, ItalyRecruiting
Unità di Ricerca e di Malattie del sangue - Ematologia S. Luca VecchioFlorence, ItalyRecruiting
AOU San Martino-IST-Ematologia 1Genova, ItalyRecruiting
Sezione di Ematologia - Ospedale S.Maria della MisericordiaPerugia, ItalyRecruiting
Dip. di Medicina Trasl. E di Precisione - U.O.C. EmatologiaRoma, ItalyRecruiting
Policlinico Tor VergataRoma, ItalyRecruiting
Ististuto Clinico Humanitas - Rozzano - Uo Oncologia Medica Ed EmatologiaRozzano, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT04587856