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Study identifier: NCT04580420 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

Condition: Primary Hyperoxaluria Type 1 · End Stage Renal Disease  ·  Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

PhasePhase 2
Planned participants28
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to evaluate DCR-PHXC in participants with PH1 and severe renal impairment, with or without dialysis.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (18)

Clinical Trial SiteSan Francisco, California, United StatesActive Not Recruiting
Clinical Trial SiteBoston, Massachusetts, United StatesActive Not Recruiting
Clinical Trial SiteRochester, Minnesota, United StatesRecruiting
Clinical Trial SiteNew York, New York, United StatesActive Not Recruiting
Clinical Trial SiteBron, FranceWithdrawn
Clinical Trial SiteParis, FranceWithdrawn
Clinical Trial SiteBonn, GermanyRecruiting
Clinical Trial SiteHeidelberg, GermanyWithdrawn
Clinical Trial SiteRoma, ItalyWithdrawn
Clinical Trial SiteBeirut, LebanonRecruiting
Clinical Trial SiteCasablanca, MoroccoWithdrawn
Clinical Trial SiteOradea, RomaniaWithdrawn

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04580420