Condition: Breast Cancer · HER2-negative Breast Cancer · Metastatic Breast Cancer · Sponsor: University of Wisconsin, Madison
The purpose of this research is to determine the expression of prostate specific membrane antigen (PSMA) in human epidermal growth factor receptor 2 (HER2)-negative, androgen receptor (AR)-positive metastatic breast cancer, and to determine its role in resistance to the anti-androgen, bicalutamide. The investigators hypothesize that PSMA expression will correlate with resistance to anti-androgen therapies, as has been documented in prostate cancer, and this can be used to select patients most likely to benefit from these therapies in future clinical trials. 15 people with HER2-negative, AR-positive metastatic breast cancer will be enrolled and be on study for about 3 days.
This description comes directly from the study's public registry record.
Radiology Studies · 608-282-8349 · radstudy@uwhealth.org
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| University of Wisconsin School of Medicine and Public Health | Madison, Wisconsin, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04573231