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Study identifier: NCT04570943 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

Condition: Locally Advanced Pancreatic Adenocarcinoma  ·  Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle

PhasePhase 2
Planned participants103
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The aim of this study is to demonstrate the efficacy of intensified and sequential chemotherapy (Gabrinox) comprising Gembrax regimen (Gemcitabine-Abraxane) followed by the Folfirinox regimen (5FU, Oxaliplatin and Irinotecan) in patients with locally advanced pancreatic adenocarcinoma. The study will also demonstrate the feasibility of combining this intensified chemotherapy with MRI-guided stereotactic radiotherapy in non-progressive patients after the chemotherapy by Gabrinox regimen.

This description comes directly from the study's public registry record.

Talk to the study team

Aurore MOUSSION, MD  ·  0467612446  ·  Aurore.Moussion@icm.unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (9)

Institut Paoli CalmettesMarseille, Bouches-du-Rhône, FranceRecruiting
CHU CarémeauNîmes, Gard, FranceRecruiting
CHU Saint-EloiMontpellier, Herault, FranceRecruiting
Institut régional du Cancer de MontpellierMontpellier, Hérault, FranceRecruiting
Hôpital BeaujonClichy, FranceNot Yet Recruiting
Centre Georges-François LeclercDijon, FranceRecruiting
Hôpital Pitié SalpétriêreParis, FranceRecruiting
Centre Eugène MarquisRennes, FranceNot Yet Recruiting
Hopital Paul BrousseVillejuif, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04570943