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Study identifier: NCT04565483 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Predictive Signature of Benralizumab Response

Condition: Asthma; Eosinophilic · Severe Asthma  ·  Sponsor: Nantes University Hospital

PhasePhase 4
Planned participants220
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The objective of the study is to establish the predictive value of early blood gene expression signature of Benralizumab response associated with a significant reduction of the number of exacerbations in treated severe asthmatic patients. This trial is a French, multicenter and no-randomized trial. Patients enrolled will be clinically followed for 16 months (the treatment period: 12 months and 1 month follow-up; 6 clinical visit on site and in phone call at 13 months)

This description comes directly from the study's public registry record.

Talk to the study team

François-Xavier BLANC, MD-PHD  ·  +33240165545  ·  xavier.blanc@chu-nantes.fr

Always discuss trial participation with your own doctor first.

Locations (20)

Centre hospitalier Intercommunal Aix-en-ProvenceAix-en-Provence, FranceRecruiting
CHU AngersAngers, FranceRecruiting
CHU BordeauxBordeaux, FranceRecruiting
CHRU BrestBrest, FranceRecruiting
CHU DijonDijon, FranceRecruiting
CHU GrenobleGrenoble, FranceRecruiting
Hôpital Bicêtre - AP-HPLe Kremlin-Bicêtre, FranceRecruiting
CH MansLe Mans, FranceWithdrawn
CHU LilleLille, FranceWithdrawn
Hospices Civils de LyonLyon, FranceRecruiting
Assistance Publique des Hôpitaux de MarseilleMarseille, FranceNot Yet Recruiting
CHU MontpellierMontpellier, FranceWithdrawn

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04565483