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Study identifier: NCT04558593 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Surveillance of Complex Renal Cysts - The SOCRATIC Study

Condition: Complex Renal Cyst  ·  Sponsor: Université de Sherbrooke

PhaseN/A
Planned participants330
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

One third of individuals aged \>60 years will be diagnosed with at least one renal cyst following abdominal imaging. These cystic lesions are categorized according to the Bosniak classification which categorizes cysts according to their degree of complexity and risk of malignancy. Growing evidence suggests that a significant proportion of Bosniak III and IV cysts are benign and that the malignant ones present low metastatic potential. Since renal surgery carries substantial morbidity (20%) and potential mortality (0.5%), active surveillance has gained attention as a potential tradeoff to surgery to overcome overtreatment. Therefore, prospective studies of long-term follow-up are needed to confirm the oncologic safety of this strategy for patients with Bosniak III/IV cysts. This is an multicenter prospective observational longitudinal study. The main objective is to compare the 5-year follow-up cancer-specific survival between the active surveillance and the surgical groups.

This description comes directly from the study's public registry record.

Talk to the study team

Amelie Tetu  ·  819-346-1110  ·  amelie.tetu.ciussse-chus@ssss.gouv.qc.ca

Always discuss trial participation with your own doctor first.

Locations (18)

Prostate Cancer CenterCalgary, Alberta, CanadaRecruiting
Northern Alberta Urology CenterEdmonton, Alberta, CanadaRecruiting
Vancouver Prostate CentreVancouver, British Columbia, CanadaRecruiting
Mens Health ClinicWinnipeg, Manitoba, CanadaRecruiting
Nova Scotia Health AuthorityHalifax, Nova Scotia, CanadaRecruiting
St-Joseph's HospitalHamilton, Ontario, CanadaRecruiting
The Ottawa HospitalOttawa, Ontario, CanadaRecruiting
Thunder Bay Health Sciences CenterThunder Bay, Ontario, CanadaRecruiting
Princess Margaret HospitalToronto, Ontario, CanadaRecruiting
Woodstock hospitalWoodstock, Ontario, CanadaRecruiting
Centre intégré de santé et de services sociaux de Chaudière-Appalaches - Hôtel-Dieu de LévisLévis, Quebec, CanadaRecruiting
CHUMMontreal, Quebec, CanadaRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT04558593