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Study identifier: NCT04550377 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI

Condition: Post Traumatic Stress Disorder · Traumatic Brain Injury  ·  Sponsor: NYU Langone Health

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This will be a randomized placebo controlled study to test the efficacy of cannabidiol (CBD) as a treatment for symptoms of post-traumatic stress disorder (PTSD). Subjects, 120 in total, will be males and females with PTSD, half of which will have comorbid mild traumatic brain injury (TBI). There will be three study arms, each with 40 subjects: 1) Oral CBD 400 mg daily; 2) Oral CBD 800 mg daily, and 3) Placebo daily. Treatment duration will be 8 weeks. The primary outcome will be change in PTSD symptoms as measured by change in the Clinician-Administered PTSD Scale (CAPS-5) total score.

This description comes directly from the study's public registry record.

Talk to the study team

Esther Blessing, MD PhD  ·  646-754-4808  ·  Esther.Blessing@nyulangone.org

Always discuss trial participation with your own doctor first.

Locations (1)

New York University School of MedicineNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04550377