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Study identifier: NCT04547166 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Clinical Study to Evaluate Efficacy and Safety of Serplulimab(HLX10) Combined With Bevacizumab(HLX04) and Chemotherapy (XELOX) in Patients With Metastatic Colorectal Cancer (mCRC)

Condition: Metastatic Colorectal Cancer  ·  Sponsor: Shanghai Henlius Biotech

PhasePhase 2/Phase 3
Planned participants568
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a two-arm, randomized, double-blinded, multicenter phase III clinical study to evaluate the clinical efficacy of Serplulimab (HLX10) in Combination With Bevacizumab and Chemotherapy (XELOX) Versus Placebo in Combination With Bevacizumab and Chemotherapy (XELOX) in First-line Treatment of Patients With Metastatic Colorectal Cancer (mCRC)

This description comes directly from the study's public registry record.

Talk to the study team

Ruihua Xu  ·  020-87343292  ·  xurh@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (5)

Center for Cancer Prevention and Treatment of Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting
Zhejiang Cancer HospitalHangzhou, Zhejiang, ChinaRecruiting
Linyi Cancer HospitalLinyi, ChinaRecruiting
Fudan University Affiliated Oncology HospitalShanghai, ChinaRecruiting
National Cancer CenterKashiwa, JapanNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT04547166