Condition: Squamous Cell Carcinoma of Head and Neck · Sponsor: Centre Henri Becquerel
Post-operative concomitant radiochemotherapy is a treatment that is difficult to achieve for several reasons. First of all, and by definition, these patients have had recent surgery, most often accompanied by several weeks of hospitalization and weight loss. In addition, the functional recovery of feeding capacity is not always complete at the time of the start of irradiation. In addition, concomitant radiochemotherapy is responsible for very frequent radiomucitus which alters the feeding capacity of patients during treatment. In total, the rate of complete radiochemotherapy (3 cures of cisplatin administered) varies from 50 to 70% depending on the studies, which were carried out in selected populations within the framework of an experimental clinical trial and without distinguishing between positive and negative Human Papilloma tumours . In our experience, in a population with a very high preponderance of non-Human Papilloma-related tumours and not selected by participation in an experimental trial, complete radiochemotherapy is only possible in about 40% to 50% of cases.However, the amount of cisplatin actually administered is correlated with overall survival. Therefore, it is logical to assume that increasing the number of patients receiving full treatment may result in increased survival. While the need for nutritional care during radiotherapy is clearly established, its modality remains debated. Recently, a randomised study of 159 patients treated by radiotherapy (or r…
This description comes directly from the study's public registry record.
Florian Clatot, MD,PhD · +33232082231 · florian.clatot@chb.unicancer.fr
Doriane Richard, PhD · +33232082985 · doriane.richard@chb.unicancer.fr
Always discuss trial participation with your own doctor first.
| CHU Amiens | Amiens, France | Recruiting |
| CH Beauvais | Beauvais, France | Recruiting |
| Clinique du Parc | Caen, France | Not Yet Recruiting |
| Centre Guillaume le Conquérant | Le Havre, France | Recruiting |
| CHRU Lille | Lille, France | Recruiting |
| Centre Henri Becquerel | Rouen, France | Recruiting |
| CH Saint-Quentin | Saint-Quentin, France | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT04528420