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Study identifier: NCT04521881 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults

Condition: Traumatic Brain Injury  ·  Sponsor: London School of Hygiene and Tropical Medicine

PhasePhase 3
Planned participants5000
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Tranexamic acid (TXA) reduces head injury deaths. The CRASH-4 trial aims to assess the effects of early intramuscular TXA on intracranial haemorrhage, disability, death, and dementia in older adults with symptomatic mild head injury

This description comes directly from the study's public registry record.

Talk to the study team

Haleema Shakur-Still  ·  +4407714139500  ·  Haleema.Shakur@lshtm.ac.uk

Always discuss trial participation with your own doctor first.

Locations (2)

The Royal London HospitalLondon, London, United KingdomRecruiting
St George's HospitalLondon, London, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT04521881