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Study identifier: NCT04520217 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Testing Use of Topical Imipramine in Reducing Ultraviolet B Induced Microvesicle Particle Release in Photosensitive Subjects

Condition: Photosensitivity · Microvesicle Particle  ·  Sponsor: Wright State University

PhasePhase 1
Planned participants40
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersYes

About this study

The purpose of this study is three-fold. First, researchers will assess whether subjects who have clinically abnormal reactions to sunlight (photosensitivity) have increased levels of microvesicle particles (MVP) following ultraviolet B (UVB) treatment to localized area of skin. Second, researchers will assess if topical application of the medicine imipramine will block UVB-induced MVP release. Third, researchers will assess if the topical cream will block UVB-induced increased erythema reactions (reddening of the skin).

This description comes directly from the study's public registry record.

Talk to the study team

Manager Clinical Research Operations  ·  937-245-7500  ·  pturesearch@wrightstatephysicians.org

Regulatory Specialist  ·  937-245-7500  ·  pturesearch@wrightstatephysicians.org

Always discuss trial participation with your own doctor first.

Locations (1)

Wright State PhysiciansFairborn, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04520217