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Study identifier: NCT04520178 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of 5HTP on the Injured Human Spinal Cord

Condition: Spinal Cord Injuries  ·  Sponsor: University of Alberta

PhasePhase 2/Phase 3
Planned participants30
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study will assess how the serotonin precursor, 5-HTP, alter nervous system excitability and motor function in individuals with spinal cord injuries of differing chronicity and severity. Participants will visit the lab on 4 separate occasions where they will be administered four different drugs in a randomized, double-blinded, placebo-controlled crossover design.

This description comes directly from the study's public registry record.

Talk to the study team

Jessica D'Amico, PhD  ·  780-735-7917  ·  damico1@ualberta.ca

Always discuss trial participation with your own doctor first.

Locations (2)

University of LouisvilleLouisville, Kentucky, United StatesCompleted
University of AlbertaEdmonton, Alberta, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT04520178