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Study identifier: NCT04520139 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

Condition: Ovarian Cancer · Cognitive Impairment  ·  Sponsor: University of California, Irvine

PhasePhase 1/Phase 2
Planned participants102
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase I, dose-escalation and phase II dose-expansion clinical trial determining the maximum tolerated dose (MTD) and safety and tolerability of adding N-Acetyl-Cysteine (NAC) to ovarian cancer patients who are receiving a platinum-based therapy (PBT). This study will investigate whether NAC will mitigate chemotherapy-related cognitive impairment (CRCI).

This description comes directly from the study's public registry record.

Talk to the study team

Chao Family Comprehensive Cancer Center University of California, Irvine  ·  1-877-827-7883  ·  ucstudy@uci.edu

University of California Irvine Medical

Always discuss trial participation with your own doctor first.

Locations (1)

Chao Family Comprehensive Cancer Center, University of California, IrvineOrange, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT04520139