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Study identifier: NCT04520074 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Adjuvant Chemotherapy of Three-step Regimen in BRCA1/2 Wide Type Ovarian Cancer (ACTS-2)

Condition: Ovarian Cancer  ·  Sponsor: Fudan University

PhasePhase 3
Planned participants590
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

Ovarian cancer was mostly diagnosed at late stage (III/IV) with high rate of recurrence after first line of therapy by optimal cytoreductive sugery and 6cycle of TP chemotherapy. There is no standard maintainance therapy for BRCA1/2 wide-type ovarian cancer. We developed an adjuvant chemotherapy of "three steps" (ACTS). It is adding CTX+VP-16(second step) 6cycle and CTX+CBP(third steps) to firstline chemotherapy (first step). The aim of this study is to verify the effectivity and safety of ACTS in BRCA1/2 wide-type ovarian cancer patients.

This description comes directly from the study's public registry record.

Talk to the study team

zhong zheng, dr  ·  862164175590  ·  alizheng@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Wu XiaohuaShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04520074