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Study identifier: NCT04519905 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase III Study of Concurrent Radiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma (ESO-Shanghai 15)

Condition: Esophageal Squamous Cell Carcinoma · Chemoradiotherapy · Survival  ·  Sponsor: Fudan University

PhaseNA
Planned participants320
Who can joinAll sexes, 76 Years to no upper limit
Healthy volunteersNo

About this study

So far, there is no specific clinical guideline for elderly patients (\>75 yr) with esophageal squamous cell carcinoma (ESCC). Patients with locally advanced ESCC were enrolled and randomly assigned to either definitive radiotherapy group (61.2Gy/34Fx) or the chemoradiotherapy group (50.4Gy/28Fx;Paclitaxel plus carboplatin). The primary end point was 3-year overall survival (OS). The second end points included life quality, radiation side effects and 3-yr cancer specific survival.

This description comes directly from the study's public registry record.

Talk to the study team

Kuaile Zhao, doctor  ·  18017312534  ·  kuaile_z@sina.com

ying jia Deng, doctor  ·  18017312829  ·  dengjiaying3@sina.com

Always discuss trial participation with your own doctor first.

Locations (3)

Jiangsu Cancer HospitalNanjing, Jiangsu, ChinaRecruiting
Huadong HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Fudan Universtiy Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04519905