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Study identifier: NCT04518501 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Fuzuloparib Arsenic Trioxide Platinum Resistance Relapsed Ovarian Cancer

Condition: Efficacy and Safety  ·  Sponsor: Xing Xie

PhasePhase 1/Phase 2
Planned participants50
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

Ovarian cancer is the leading cause of death from gynecologic tumors in the western world. Most patients have relapses, and responses to subsequent therapies are generally short-lived. Currently, the population that can benefit from PARPi is mainly focusing on BRCAm, then homologous-recombination deficiency patients. Limited data revealed the ORR was only 3-4% in homologous recombination proficiency patients with PARPi therapy. New treatments are urgently needed to improve patient outcomes. To explore the efficacy and safety of Fuzuloparib in combination with Arsenic trioxide therapy in platinum-resistance relapsed Ovarian cancer patients.

This description comes directly from the study's public registry record.

Talk to the study team

yuanming shen, PhD  ·  13588193832  ·  13588193832@163.com

xing xie, PhD  ·  13606705128  ·  xiex@zju.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Women's Hospital School Of Medicine Zhejiang UniversityZhejiang, Hangzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT04518501